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ATTR-CM is short for transthyretin amyloid cardiomyopathy, a type of cardiac amyloidosis

Cardiac amyloidosis is a disorder caused by deposits of an abnormal protein, also known as ‘amyloid’, in the heart tissue. Over time, these proteins replace normal tissue and make it hard for the heart to work properly, leading to heart failure.1–3

ATTR-CM is associated with a specific protein called transthyretin, which when unstable, loses its structure and forms amyloid fibrils (small or thin fibres) that get deposited in the heart. ATTR-CM can be life-threatening and is often underdiagnosed and untreated, which may lead to heart failure.1,2,4

When you have ATTR-CM
When you have ATTR-CM
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  16. Australian Amyloidosis Network. ATTR amyloidosis. www.amyloidosis.net.au/health-professionals/amyloidosis-types/attr/ Accessed May 2020.